Cryptonews Industry Talk

Is PEPE About to Flip Ethereum? This Breakout Has Traders Ditching ETH Fast

Ethereum Pepe Price Prediction

Pepe is on the breakout path, and traders are beginning to eye it for the altcoin throne as it climbs the top 100.

Junior Content Creator

Harvey Hunter

Junior Content Creator

Harvey Hunter

About Author

Harvey Hunter is a Junior Content Creator at Cryptonews.com. With a background in Computer Science, IT, and Mathematics, he seamlessly transitioned from tech geek to crypto journalist.

Author Profile

Last updated:

April 21, 2025

Why Trust Cryptonews

Cryptonews has covered the cryptocurrency industry topics since 2017, aiming to provide informative insights to our readers. Our journalists and analysts have extensive experience in market analysis and blockchain technologies. We strive to maintain high editorial standards, focusing on factual accuracy and balanced reporting across all areas - from cryptocurrencies and blockchain projects to industry events, products, and technological developments. Our ongoing presence in the industry reflects our commitment to delivering relevant information in the evolving world of digital assets. Read more about Cryptonews

Disclaimer: Crypto is a high-risk asset class. This article is provided for informational purposes and does not constitute investment advice. You could lose all of your capital.

Is PEPE About to Flip Ethereum? This Breakout Has Traders Ditching ETH Fast

PEPE has emerged as a preferred choice for traders, notching a 19% gain on the weekly while leading altcoin Ethereum logged a 1% loss.

The onboarding of pro-crypto SEC chair Paul Atkins has helped revive risk-on sentiment, prompting fresh speculation over the best crypto to buy next.

While Ethereum remains stagnant, Pepe is soaking up fresh retail liquidity—momentum is on its side.

Claim to the Throne: Can Pepe Really Flip Ethereum?

Pepe would need to 56x to surpass Ethereum at their current market caps—a stretch, but not without merit when considering long-term potential.

Recent Santiment data shows a sharp decline in exchange-held supply, dropping from 45% in November to just 28.9% today. This shift toward self-custody suggests growing conviction among long-term holders.

PEPE on-chian data. Source: Santiment. — PEPE on-chain data. Source: Santiment.

More so, whale addresses have boosted their holdings from 116 trillion to 150 trillion tokens.

Such accumulation patterns often serve as early indicators of a broader rally. Big players tend to move before the crowd, and their growing interest in Pepe adds fuel to the bullish narrative.

PEPE Price Analysis: Breakout Eyes New High

According to the analysis shared on the TradingView platform, a descending channel breakout reminiscent of the one that ran from May to September 2024 could lead the next leg up.

PEPE / USDT 1-day chart, descending channel pattern breakout. Source: Master Ananda / TradingView.

The formation that preceded PEPE’s late 2024 breakout to new all-time highs is repeating, laying the groundwork for what could be an explosive run.

Two distinct swing highs and lows have shaped what appears to be a reversal structure, in line with a long-term support zone that has guided lows since mid-2024.

A new higher low is beginning to form—a precursor to bullish continuation based on past price action.

Momentum indicators back the case: the MACD line nears a golden cross above the signal line, while the weekly Relative Strength Index (RSI) trends higher at 43, approaching the neutral midpoint.

A credible scenario as the MACD line nears a golden cross, en route to surpass the signal line, while the Relative Strength Index (RSI) trends closer towards neutral on the weekly chart.

The analysis highlights strong confluence with Fibonacci extension levels, with the 1.618 Fib level suggesting a possible 480% move to $0.0000426.

However, the more ambitious 2.618 extension points to an 800% upside to $0.00006575—potentially in play before the end of 2025.

While PEPE Eyes an 8x, This New ICO Eyes 100xs

Sidelined investors may have one final opportunity to buy PEPE before its next explosive rally, but at its $3B market cap, its biggest gains are behind it.

That’s where MIND of Pepe ($MIND) steps in, giving traders a chance to get in early and stay ahead of high-gaining opportunities before they go mainstream.

The MIND of Pepe AI will actively engage with the crypto community through X—driving conversations, uncovering alpha opportunities, and delivering exclusive, token-gated insights.

Inside its Telegram community, holders get early access to high-potential tokens before they hit the market, keeping them ahead of the curve.

At the time of writing, MIND has raised over $8.1 million in its ongoing presale, capitalizing on the Pepe brand and one of this cycle’s strongest meme coin narratives: AI agents.