Lost Bitcoin and the Deflationary Experiment

In this video, educator Andreas M. Antonopoulos answers the following questions: Do you think it is a problem that Bitcoin private keys can be destroyed, in terms of a store-of-value? Should we re-distribute bitcoin which hasn't moved for a long period of time? Should we do something about lost coins? Is there potential for centralization through concentration of ownership of bitcoin? Has there ever been a deflationary experiment? Wouldn't people stop spending altogether?